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Targeted ablation of NrCAM or ankyrin-B results in disorganized lens fibers leading to cataract formation
The NgCAM-related cell adhesion molecule (NrCAM) is an immunoglobulin superfamily member of the L1 subgroup that interacts intracellularly with ankyrins. We reveal that the absence of NrCAM causes the formation of mature cataracts in the mouse, whereas significant pathfinding errors of commissural a...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2001
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196853/ https://www.ncbi.nlm.nih.gov/pubmed/11449000 http://dx.doi.org/10.1083/jcb.200104038 |