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Correction of Population Stratification in Large Multi-Ethnic Association Studies
BACKGROUND: The vast majority of genetic risk factors for complex diseases have, taken individually, a small effect on the end phenotype. Population-based association studies therefore need very large sample sizes to detect significant differences between affected and non-affected individuals. Inclu...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2198793/ https://www.ncbi.nlm.nih.gov/pubmed/18196181 http://dx.doi.org/10.1371/journal.pone.0001382 |