Correction of Population Stratification in Large Multi-Ethnic Association Studies

BACKGROUND: The vast majority of genetic risk factors for complex diseases have, taken individually, a small effect on the end phenotype. Population-based association studies therefore need very large sample sizes to detect significant differences between affected and non-affected individuals. Inclu...

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Detalles Bibliográficos
Autores principales: Serre, David, Montpetit, Alexandre, Paré, Guillaume, Engert, James C., Yusuf, Salim, Keavney, Bernard, Hudson, Thomas J., Anand, Sonia
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2198793/
https://www.ncbi.nlm.nih.gov/pubmed/18196181
http://dx.doi.org/10.1371/journal.pone.0001382

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