Apoptotic death of neurons exhibiting peripherin aggregates is mediated by the proinflammatory cytokine tumor necrosis factor-α

Peripherin, a neuronal intermediate filament protein associated with axonal spheroids in amyotrophic lateral sclerosis (ALS), induces the selective degeneration of motor neurons when overexpressed in transgenic mice. To further clarify the selectivity and mechanism of peripherin-induced neuronal dea...

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Detalles Bibliográficos
Autores principales: Robertson, Janice, Beaulieu, Jean-Martin, Doroudchi, Mohammad M., Durham, Heather D., Julien, Jean-Pierre, Mushynski, Walter E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2198840/
https://www.ncbi.nlm.nih.gov/pubmed/11604419
http://dx.doi.org/10.1083/jcb.200107058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2198840/
https://www.ncbi.nlm.nih.gov/pubmed/11604419
http://dx.doi.org/10.1083/jcb.200107058

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