Ectodomain shedding of L1 adhesion molecule promotes cell migration by autocrine binding to integrins

The L1 adhesion molecule plays an important role in axon guidance and cell migration in the nervous system. L1 is also expressed by many human carcinomas. In addition to cell surface expression, the L1 ectodomain can be released by a metalloproteinase, but the biological function of this process is...

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Detalles Bibliográficos
Autores principales: Mechtersheimer, Sabine, Gutwein, Paul, Agmon-Levin, Nancy, Stoeck, Alexander, Oleszewski, Matthias, Riedle, Svenja, Postina, Rolf, Fahrenholz, Falk, Fogel, Mina, Lemmon, Vance, Altevogt, Peter
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2198870/
https://www.ncbi.nlm.nih.gov/pubmed/11706054
http://dx.doi.org/10.1083/jcb.200101099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2198870/
https://www.ncbi.nlm.nih.gov/pubmed/11706054
http://dx.doi.org/10.1083/jcb.200101099

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