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Ectodomain shedding of L1 adhesion molecule promotes cell migration by autocrine binding to integrins
The L1 adhesion molecule plays an important role in axon guidance and cell migration in the nervous system. L1 is also expressed by many human carcinomas. In addition to cell surface expression, the L1 ectodomain can be released by a metalloproteinase, but the biological function of this process is...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2001
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2198870/ https://www.ncbi.nlm.nih.gov/pubmed/11706054 http://dx.doi.org/10.1083/jcb.200101099 |