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Ablation of Cypher, a PDZ-LIM domain Z-line protein, causes a severe form of congenital myopathy

Cypher is a member of a recently emerging family of proteins containing a PDZ domain at their NH(2) terminus and one or three LIM domains at their COOH terminus. Cypher knockout mice display a severe form of congenital myopathy and die postnatally from functional failure in multiple striated muscles...

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Detalles Bibliográficos
Autores principales: Zhou, Qiang, Chu, Po-Hsien, Huang, Chenqun, Cheng, Ching-Feng, Martone, Maryann E., Knoll, Gudrun, Shelton, G. Diane, Evans, Sylvia, Chen, Ju
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2198871/
https://www.ncbi.nlm.nih.gov/pubmed/11696561
http://dx.doi.org/10.1083/jcb.200107092