α-Toxin is a mediator of Staphylococcus aureus–induced cell death and activates caspases via the intrinsic death pathway independently of death receptor signaling

Infections with Staphylococcus aureus, a common inducer of septic and toxic shock, often result in tissue damage and death of various cell types. Although S. aureus was suggested to induce apoptosis, the underlying signal transduction pathways remained elusive. We show that caspase activation and DN...

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Detalles Bibliográficos
Autores principales: Bantel, Heike, Sinha, Bhanu, Domschke, Wolfram, Peters, Georg, Schulze-Osthoff, Klaus, Jänicke, Reiner U.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2198876/
https://www.ncbi.nlm.nih.gov/pubmed/11696559
http://dx.doi.org/10.1083/jcb.200105081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2198876/
https://www.ncbi.nlm.nih.gov/pubmed/11696559
http://dx.doi.org/10.1083/jcb.200105081

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