Class I–restricted Cross-Presentation of Exogenous Self-Antigens Leads to Deletion of Autoreactive CD8(+) T Cells

In this report, we show that cross-presentation of self-antigens can lead to the peripheral deletion of autoreactive CD8(+) T cells. We had previously shown that transfer of ovalbumin (OVA)-specific CD8(+) T cells (OT-I cells) into rat insulin promoter–membrane-bound form of OVA transgenic mice, whi...

Descripción completa

Detalles Bibliográficos
Autores principales: Kurts, Christian, Kosaka, Hiroshi, Carbone, Francis R., Miller, Jacques F.A.P., Heath, William R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2198972/
https://www.ncbi.nlm.nih.gov/pubmed/9221753

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2198972/
https://www.ncbi.nlm.nih.gov/pubmed/9221753

Ejemplares similares