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Negative Signaling Pathways of the Killer Cell Inhibitory Receptor and FcγRIIb1 Require Distinct Phosphatases

Inhibition of natural killer (NK) cells by the killer cell inhibitory receptor (KIR) involves recruitment of the tyrosine phosphatase SHP-1 by KIR and is prevented by expression of a dominant negative SHP-1 mutant. Another inhibitory receptor, the low affinity Fc receptor for immunoglobulin G (IgG)...

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Detalles Bibliográficos
Autores principales: Gupta, Neetu, Scharenberg, Andrew M., Burshtyn, Deborah N., Wagtmann, Nicolai, Lioubin, Mario N., Rohrschneider, Larry R., Kinet, Jean-Pierre, Long, Eric O.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199004/
https://www.ncbi.nlm.nih.gov/pubmed/9236201