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Negative Signaling Pathways of the Killer Cell Inhibitory Receptor and FcγRIIb1 Require Distinct Phosphatases
Inhibition of natural killer (NK) cells by the killer cell inhibitory receptor (KIR) involves recruitment of the tyrosine phosphatase SHP-1 by KIR and is prevented by expression of a dominant negative SHP-1 mutant. Another inhibitory receptor, the low affinity Fc receptor for immunoglobulin G (IgG)...
Autores principales: | Gupta, Neetu, Scharenberg, Andrew M., Burshtyn, Deborah N., Wagtmann, Nicolai, Lioubin, Mario N., Rohrschneider, Larry R., Kinet, Jean-Pierre, Long, Eric O. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1997
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199004/ https://www.ncbi.nlm.nih.gov/pubmed/9236201 |
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