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Disruption of the Bcl6 Gene Results in an Impaired Germinal Center Formation

The Bcl6 gene has been identified from the chromosomal translocation breakpoint in B cell lymphomas, and its products are expressed highly in germinal center (GC) B cells. To investigate the function of Bcl6 in lymphocytes, we have generated RAG1-deficient mice reconstituted with bone marrow cells f...

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Detalles Bibliográficos
Autores principales: Fukuda, Tetsuya, Yoshida, Takehiko, Okada, Seiji, Hatano, Masahiko, Miki, Tohru, Ishibashi, Kazuki, Okabe, Shinichiro, Koseki, Haruhiko, Hirosawa, Shinsaku, Taniguchi, Masaru, Miyasaka, Nobuyuki, Tokuhisa, Takeshi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199007/
https://www.ncbi.nlm.nih.gov/pubmed/9236196