The Motheaten Mutation Rescues B Cell Signaling and Development in CD45-deficient Mice

The cytosolic SHP-1 and transmembrane CD45 protein tyrosine phosphatases (PTP) play critical roles in regulating signal transduction via the B cell antigen receptor (BCR). These PTPs differ, however, in their effects on BCR function. For example, BCR-mediated mitogenesis is essentially ablated in mi...

Descripción completa

Detalles Bibliográficos
Autores principales: Pani, Giovanni, Siminovitch, Katherine A., Paige, Christopher J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199033/
https://www.ncbi.nlm.nih.gov/pubmed/9254656

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199033/
https://www.ncbi.nlm.nih.gov/pubmed/9254656

Ejemplares similares