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Two Distinct Steps during Thymocyte Maturation from CD4(−)CD8(−) to CD4(+)CD8(+) Distinguished in the Early Growth Response (Egr)-1 Transgenic Mice with a Recombinase-activating Gene–Deficient Background
The early growth response (Egr)-1 is a zinc finger–containing transcription factor belonging to the immediate–early genes. Its expression in CD4/CD8 double negative (DN) immature thymocytes suggests that Egr-1 expression may be involved in early thymocyte development. In transgenic mice overexpressi...
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| Formato: | Texto |
| Lenguaje: | English |
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The Rockefeller University Press
1997
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199048/ https://www.ncbi.nlm.nih.gov/pubmed/9294142 |