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Generation of Lytic Natural Killer 1.1(+), Ly-49(−) Cells from Multipotential Murine Bone Marrow Progenitors in a Stroma-free Culture: Definition of Cytokine Requirements and Developmental Intermediates

We have developed a stroma-free culture system in which mouse marrow or thymus cells, known to be enriched for lymphoid progenitors, can be driven to generate natural killer (NK) cells. Culture of lineage marker (Lin)(−), c-kit(+), Sca2(+), interleukin (IL)-2/15Rβ (CD122)(−) marrow cells in IL-6, IL...

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Detalles Bibliográficos
Autores principales: Williams, Noelle Sevilir, Moore, Thomas A., Schatzle, John D., Puzanov, Igor J., Sivakumar, P.V., Zlotnik, Albert, Bennett, Michael, Kumar, Vinay
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199105/
https://www.ncbi.nlm.nih.gov/pubmed/9348320