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Inhibition of T Cell and Promotion of Natural Killer Cell Development by the Dominant Negative Helix Loop Helix Factor Id3

Bipotential T/natural killer (NK) progenitor cells are present in the human thymus. Despite their bipotential capacity, these progenitors develop predominantly to T cells in the thymus. The mechanisms controlling this developmental choice are unknown. Here we present evidence that a member(s) of the...

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Detalles Bibliográficos
Autores principales: Heemskerk, Mirjam H.M., Blom, Bianca, Nolan, Garry, Stegmann, Alexander P.A., Bakker, Arjen Q., Weijer, Kees, Res, Pieter C.M., Spits, Hergen
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199115/
https://www.ncbi.nlm.nih.gov/pubmed/9348318