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Critical Points of Tumor Necrosis Factor Action in Central Nervous System Autoimmune Inflammation Defined by Gene Targeting

Tumor necrosis factor (TNF)–dependent sites of action in the generation of autoimmune inflammation have been defined by targeted disruption of TNF in the C57BL/6 mouse strain. C57BL/6 mice are susceptible to an inflammatory, demyelinating form of experimental autoimmune encephalomyelitis (EAE) induc...

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Detalles Bibliográficos
Autores principales: Körner, Heinrich, Riminton, D. Sean, Strickland, Deborah H., Lemckert, Frances A., Pollard, John D., Sedgwick, Jonathon D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199118/
https://www.ncbi.nlm.nih.gov/pubmed/9348316