Cargando…

Critical Points of Tumor Necrosis Factor Action in Central Nervous System Autoimmune Inflammation Defined by Gene Targeting

Tumor necrosis factor (TNF)–dependent sites of action in the generation of autoimmune inflammation have been defined by targeted disruption of TNF in the C57BL/6 mouse strain. C57BL/6 mice are susceptible to an inflammatory, demyelinating form of experimental autoimmune encephalomyelitis (EAE) induc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Körner, Heinrich, Riminton, D. Sean, Strickland, Deborah H., Lemckert, Frances A., Pollard, John D., Sedgwick, Jonathon D.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1997
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199118/ https://www.ncbi.nlm.nih.gov/pubmed/9348316

Ejemplares similares

Challenging Cytokine Redundancy: Inflammatory Cell Movement and Clinical Course of Experimental Autoimmune Encephalomyelitis Are Normal in Lymphotoxin-deficient, but Not Tumor Necrosis Factor–deficient, Mice
por: Sean Riminton, D., et al.
Publicado: (1998)

Generation of Splenic Follicular Structure and B Cell Movement in Tumor Necrosis Factor–deficient Mice
por: Cook, Matthew C., et al.
Publicado: (1998)

Lymphotoxin α/β and Tumor Necrosis Factor Are Required for Stromal Cell Expression of Homing Chemokines in B and T Cell Areas of the Spleen
por: Ngo, Vu N., et al.
Publicado: (1999)

Divergent Pro- and Antiinflammatory Roles for IL-23 and IL-12 in Joint Autoimmune Inflammation
por: Murphy, Craig A., et al.
Publicado: (2003)

An Essential Role for Tumor Necrosis Factor in Natural Killer Cell–mediated Tumor Rejection in the Peritoneum
por: Smyth, Mark J., et al.
Publicado: (1998)

Tumor Necrosis Factor Sustains the Generalized Lymphoproliferative Disorder ( gld ) Phenotype
por: Körner, Heinrich, et al.
Publicado: (2000)

Secreted Lymphotoxin-α Is Essential for the Control of an Intracellular Bacterial Infection
por: Roach, Daniel R., et al.
Publicado: (2001)

Tumor Necrosis Factor α and Lymphotoxin α Are Not Required for Induction of Acute Experimental Autoimmune Encephalomyelitis
por: Frei, Karl, et al.
Publicado: (1997)

Peroxisome proliferator–activated receptor δ limits the expansion of pathogenic Th cells during central nervous system autoimmunity
por: Dunn, Shannon E., et al.
Publicado: (2010)

Increased Thymic B Cells but Maintenance of Thymic Structure, T Cell Differentiation and Negative Selection in Lymphotoxin-α and TNF Gene-Targeted Mice
por: Grech, Adrian P., et al.
Publicado: (2000)

Coupling and Uncoupling of Tumor Immunity and Autoimmunity
por: Bowne, Wilbur B., et al.
Publicado: (1999)

Human Nerve Growth Factor Protects Common Marmosets against Autoimmune Encephalomyelitis by Switching the Balance of T Helper Cell Type 1 and 2 Cytokines within the Central Nervous System
por: Villoslada, Pablo, et al.
Publicado: (2000)

ROLE OF H-2 LYMPHOCYTE-DEFINED AND SEROLOGICALLY-DEFINED COMPONENTS IN THE GENERATION OF CYTOTOXIC LYMPHOCYTES
por: Alter, Barbara J., et al.
Publicado: (1974)

Expansion of somatically reverted memory CD8(+) T cells in patients with X-linked lymphoproliferative disease caused by selective pressure from Epstein-Barr virus
por: Palendira, Umaimainthan, et al.
Publicado: (2012)

Taci Is a Traf-Interacting Receptor for Tall-1, a Tumor Necrosis Factor Family Member Involved in B Cell Regulation
por: Xia, Xing-Zhong, et al.
Publicado: (2000)

SH2D1A Regulates T-dependent Humoral Autoimmunity
por: Hron, Jonathan D., et al.
Publicado: (2004)

Resistance to Experimental Autoimmune Encephalomyelitis in Mice Lacking the Cc Chemokine Receptor (Ccr2)
por: Izikson, Leonid, et al.
Publicado: (2000)

Locally Up-regulated Lymphotoxin α, Not Systemic Tumor Necrosis Factor α, Is the Principle Mediator of Murine Cerebral Malaria
por: Engwerda, Christian R., et al.
Publicado: (2002)

Defining and diagnosing glaucoma: a focus on blindness prevention
por: Mohamed-Noriega, Jibran, et al.
Publicado: (2021)

Inflammatory Cytokine Profiles During Exercise in Obese, Diabetic, and Healthy Children
por: Galassetti, Pietro R., et al.
Publicado: (2011)

Complementary and Alternative Medicine in Children with Type 1 Diabetes Mellitus
por: Haliloglu, Belma, et al.
Publicado: (2011)

3M Syndrome: A Report of Four Cases in Two Families
por: Güven, Ayla, et al.
Publicado: (2011)

Leptin Is an Endogenous Protective Protein against the Toxicity Exerted by Tumor Necrosis Factor
por: Takahashi, Nozomi, et al.
Publicado: (1999)

A Mediator Role For Metallothionein in Tumor Necrosis Factor–induced Lethal Shock
por: Waelput, Wim, et al.
Publicado: (2001)

Gamma secretase inhibition promotes hypoxic necrosis in mouse pancreatic ductal adenocarcinoma
por: Cook, Natalie, et al.
Publicado: (2012)

Type I interferon drives tumor necrosis factor–induced lethal shock
por: Huys, Liesbeth, et al.
Publicado: (2009)

Bone Marrow–generated Dendritic Cells Pulsed with Tumor Extracts or Tumor RNA Induce Antitumor Immunity against Central Nervous System Tumors
por: Ashley, David M., et al.
Publicado: (1997)

Intracellular Adenosine Triphosphate (ATP) Concentration: A Switch in the Decision Between Apoptosis and Necrosis
por: Leist, Marcel, et al.
Publicado: (1997)

LATENT HERPES SIMPLEX VIRUS IN THE CENTRAL NERVOUS SYSTEM OF RABBITS AND MICE
por: Knotts, F. B., et al.
Publicado: (1973)

Peripheral Autoantigen Induces Regulatory T Cells that Prevent Autoimmunity
por: Seddon, Benedict, et al.
Publicado: (1999)

Role of Antigen-Presenting Cells in Mediating Tolerance and Autoimmunity
por: Garza, Kristine M., et al.
Publicado: (2000)

Delayed Apoptotic Cell Clearance and Lupus-like Autoimmunity in Mice Lacking the c-mer Membrane Tyrosine Kinase
por: Cohen, Philip L., et al.
Publicado: (2002)

APRIL, a New Ligand of the Tumor Necrosis Factor Family, Stimulates Tumor Cell Growth
por: Hahne, Michael, et al.
Publicado: (1998)

Chlamydia pneumoniae Infection of the Central Nervous System Worsens Experimental Allergic Encephalitis
por: Du, Caigan, et al.
Publicado: (2002)

Requirement of Fas for the Development of Autoimmune Diabetes in Nonobese Diabetic Mice
por: Itoh, Naoto, et al.
Publicado: (1997)

Transgenic Interleukin 10 Prevents Induction of Experimental Autoimmune Encephalomyelitis
por: Cua, Daniel J., et al.
Publicado: (1999)

Treatment of Experimental Autoimmune Encephalomyelitis with Genetically Modified Memory T Cells
por: Mathisen, Peter M., et al.
Publicado: (1997)

Loss of Roquin induces early death and immune deregulation but not autoimmunity
por: Bertossi, Arianna, et al.
Publicado: (2011)

Negative regulation of autoimmune demyelination by the inhibitory receptor CLM-1
por: Xi, Hongkang, et al.
Publicado: (2010)

Baff Binds to the Tumor Necrosis Factor Receptor–Like Molecule B Cell Maturation Antigen and Is Important for Maintaining the Peripheral B Cell Population
por: Thompson, Jeffrey S., et al.
Publicado: (2000)

Cannot write session to /tmp/vufind_sessions/sess_23vs90pte1dquf9e2d7dd7k72t