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Quantitative Contribution of CD4 and CD8 to T Cell Antigen Receptor Serial Triggering

CD4 and CD8 are thought to function as coreceptors by binding to the cognate major histocompatibility complex (MHC) molecules recognized by the T cell antigen receptor (TCR) and initiating the signal transduction cascade. We report that during T cell–antigen-presenting cell interaction, triggered TC...

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Detalles Bibliográficos
Autores principales: Viola, Antonella, Salio, Mariolina, Tuosto, Loretta, Linkert, Susanne, Acuto, Oreste, Lanzavecchia, Antonio
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199127/
https://www.ncbi.nlm.nih.gov/pubmed/9362538