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Signal Transduction Due to HIV-1 Envelope Interactions with Chemokine Receptors CXCR4 or CCR5

Infection with HIV-1 requires expression of CD4 and the chemokine receptors CXCR4 or CCR5 at the target cell surface. Engagement of these receptors by the HIV-1 envelope glycoprotein is essential for membrane fusion, but may additionally activate intracellular signaling pathways. In this study, we d...

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Detalles Bibliográficos
Autores principales: Davis, Craig B., Dikic, Ivan, Unutmaz, Derya, Hill, C. Mark, Arthos, James, Siani, Michael A., Thompson, Darren A., Schlessinger, Joseph, Littman, Dan R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199136/
https://www.ncbi.nlm.nih.gov/pubmed/9362541