Qualitative Regulation of B Cell Antigen Receptor Signaling by CD19: Selective Requirement for PI3-Kinase Activation, Inositol-1,4,5-Trisphosphate Production and Ca(2+) Mobilization

Genetic ablation of the B cell surface glycoprotein CD19 severely impairs the humoral immune response. This requirement is thought to reflect a critical role of CD19 in signal transduction that occurs upon antigen C3dg coligation of antigen receptors with CD19 containing type 2 complement receptors...

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Detalles Bibliográficos
Autores principales: Buhl, Anne Mette, Pleiman, Christopher M., Rickert, Robert C., Cambier, John C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199152/
https://www.ncbi.nlm.nih.gov/pubmed/9382888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199152/
https://www.ncbi.nlm.nih.gov/pubmed/9382888

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