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In Vivo Microbial Stimulation Induces Rapid CD40 Ligand–independent Production of Interleukin 12 by Dendritic Cells and their Redistribution to T Cell Areas

The early induction of interleukin (IL)-12 is a critical event in determining the development of both innate resistance and adaptive immunity to many intracellular pathogens. Previous in vitro studies have suggested that the macrophage (MΦ) is a major source of the initial IL-12 produced upon microb...

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Detalles Bibliográficos
Autores principales: Sousa, Caetano Reis e, Hieny, Sara, Scharton-Kersten, Tanya, Jankovic, Dragana, Charest, Hugues, Germain, Ronald N., Sher, Alan
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199158/
https://www.ncbi.nlm.nih.gov/pubmed/9382881