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Immunoproteasome Assembly: Cooperative Incorporation of Interferon γ (IFN-γ)–inducible Subunits

LMP2, LMP7, and MECL are interferon γ–inducible catalytic subunits of vertebrate 20S proteasomes, which can replace constitutive catalytic subunits (delta, X, and Z, respectively) during proteasome biogenesis. We demonstrate that MECL requires LMP2 for efficient incorporation into preproteasomes, an...

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Detalles Bibliográficos
Autores principales: Griffin, Thomas A., Nandi, Dipankar, Cruz, Miguel, Fehling, Hans Jörg, Kaer, Luc Van, Monaco, John J., Colbert, Robert A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199179/
https://www.ncbi.nlm.nih.gov/pubmed/9419215