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Immunoproteasome Assembly: Cooperative Incorporation of Interferon γ (IFN-γ)–inducible Subunits
LMP2, LMP7, and MECL are interferon γ–inducible catalytic subunits of vertebrate 20S proteasomes, which can replace constitutive catalytic subunits (delta, X, and Z, respectively) during proteasome biogenesis. We demonstrate that MECL requires LMP2 for efficient incorporation into preproteasomes, an...
Autores principales: | Griffin, Thomas A., Nandi, Dipankar, Cruz, Miguel, Fehling, Hans Jörg, Kaer, Luc Van, Monaco, John J., Colbert, Robert A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199179/ https://www.ncbi.nlm.nih.gov/pubmed/9419215 |
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