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Antigen Is Required for the Activation of Effector Activities, whereas Interleukin 2 Is Required for the Maintenance of Memory in Ovalbumin-specific, CD8(+) Cytotoxic T Lymphocytes

The mechanisms that maintain memory in T cells are not completely understood. We have investigated the role of antigen and interleukin (IL)-2 in the growth and maintenance of CD8(+) T cells using a cytolytic T cell line specific for ovalbumin (OVA)(257-264) presented by H-2K(b). This line does not s...

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Detalles Bibliográficos
Autores principales: Ke, Yong, Ma, Hakling, Kapp, Judith A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199192/
https://www.ncbi.nlm.nih.gov/pubmed/9419210