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The Class I Antigen-processing Pathway for the Membrane Protein Tyrosinase Involves Translation in the Endoplasmic Reticulum and Processing in the Cytosol

Formation of major histocompatibility complex class I–associated peptides from membrane proteins has not been thoroughly investigated. We examined the processing of an HLA-A*0201–associated epitope, YMDGTMSQV, that is derived from the membrane protein tyrosinase by posttranslational conversion of th...

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Detalles Bibliográficos
Autores principales: Mosse, Claudio A., Meadows, Leslie, Luckey, Chance J., Kittlesen, David J., Huczko, Eric L., Slingluff, Craig L., Shabanowitz, Jeffrey, Hunt, Donald F., Engelhard, Victor H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199193/
https://www.ncbi.nlm.nih.gov/pubmed/9419209