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Glial Growth Factor/Neuregulin Inhibits Schwann Cell Myelination and Induces Demyelination

During development, neuregulin-1 promotes Schwann cell proliferation and survival; its role in later events of Schwann cell differentiation, including myelination, is poorly understood. Accordingly, we have examined the effects of neuregulin-1 on myelination in neuron-Schwann cell cocultures. Glial...

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Detalles Bibliográficos
Autores principales: Zanazzi, George, Einheber, Steven, Westreich, Richard, Hannocks, Melanie-Jane, Bedell-Hogan, Debra, Marchionni, Mark A., Salzer, James L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199210/
https://www.ncbi.nlm.nih.gov/pubmed/11257128