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The integrin cytoplasmic domain-associated protein ICAP-1 binds and regulates Rho family GTPases during cell spreading

Using two-hybrid screening, we isolated the integrin cytoplasmic domain-associated protein (ICAP-1), an interactor for the COOH terminal region of the β1A integrin cytoplasmic domain. To investigate the role of ICAP-1 in integrin-mediated adhesive function, we expressed the full-length molecule in N...

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Detalles Bibliográficos
Autores principales: Degani, Simona, Balzac, Fiorella, Brancaccio, Mara, Guazzone, Simona, Retta, Saverio Francesco, Silengo, Lorenzo, Eva, Alessandra, Tarone, Guido
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199222/
https://www.ncbi.nlm.nih.gov/pubmed/11807099
http://dx.doi.org/10.1083/jcb.200108030