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The integrin cytoplasmic domain-associated protein ICAP-1 binds and regulates Rho family GTPases during cell spreading
Using two-hybrid screening, we isolated the integrin cytoplasmic domain-associated protein (ICAP-1), an interactor for the COOH terminal region of the β1A integrin cytoplasmic domain. To investigate the role of ICAP-1 in integrin-mediated adhesive function, we expressed the full-length molecule in N...
Autores principales: | Degani, Simona, Balzac, Fiorella, Brancaccio, Mara, Guazzone, Simona, Retta, Saverio Francesco, Silengo, Lorenzo, Eva, Alessandra, Tarone, Guido |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199222/ https://www.ncbi.nlm.nih.gov/pubmed/11807099 http://dx.doi.org/10.1083/jcb.200108030 |
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