Conditional gene ablation of Stat3 reveals differential signaling requirements for survival of motoneurons during development and after nerve injury in the adult

Members of the ciliary neurotrophic factor (CNTF)/leukemia inhibitory factor (LIF)/cardiotrophin gene family are potent survival factors for embryonic and lesioned motoneurons. These factors act via receptor complexes involving gp130 and LIFR-β and ligand binding leads to activation of various signa...

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Detalles Bibliográficos
Autores principales: Schweizer, Ulrich, Gunnersen, Jennifer, Karch, Christoph, Wiese, Stefan, Holtmann, Bettina, Takeda, Kiyoshi, Akira, Shizuo, Sendtner, Michael
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199226/
https://www.ncbi.nlm.nih.gov/pubmed/11807093
http://dx.doi.org/10.1083/jcb.200107009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199226/
https://www.ncbi.nlm.nih.gov/pubmed/11807093
http://dx.doi.org/10.1083/jcb.200107009

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