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Human VPS34 is required for internal vesicle formation within multivesicular endosomes

After internalization from the plasma membrane, activated EGF receptors (EGFRs) are delivered to multivesicular bodies (MVBs). Within MVBs, EGFRs are removed from the perimeter membrane to internal vesicles, thereby being sorted from transferrin receptors, which recycle back to the plasma membrane....

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Detalles Bibliográficos
Autores principales: Futter, C.E., Collinson, L.M., Backer, J.M., Hopkins, C.R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199316/
https://www.ncbi.nlm.nih.gov/pubmed/11756475
http://dx.doi.org/10.1083/jcb.200108152