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Polyploids require Bik1 for kinetochore–microtubule attachment

The attachment of kinetochores to spindle microtubules (MTs) is essential for maintaining constant ploidy in eukaryotic cells. Here, biochemical and imaging data is presented demonstrating that the budding yeast CLIP-170 orthologue Bik1is a component of the kinetochore-MT binding interface. Striking...

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Detalles Bibliográficos
Autores principales: Lin, Haijiang, de Carvalho, Pedro, Kho, David, Tai, Chin-Yin, Pierre, Philippe, Fink, Gerald R., Pellman, David
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199317/
https://www.ncbi.nlm.nih.gov/pubmed/11756471
http://dx.doi.org/10.1083/jcb.200108119