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Polyploids require Bik1 for kinetochore–microtubule attachment
The attachment of kinetochores to spindle microtubules (MTs) is essential for maintaining constant ploidy in eukaryotic cells. Here, biochemical and imaging data is presented demonstrating that the budding yeast CLIP-170 orthologue Bik1is a component of the kinetochore-MT binding interface. Striking...
Autores principales: | Lin, Haijiang, de Carvalho, Pedro, Kho, David, Tai, Chin-Yin, Pierre, Philippe, Fink, Gerald R., Pellman, David |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199317/ https://www.ncbi.nlm.nih.gov/pubmed/11756471 http://dx.doi.org/10.1083/jcb.200108119 |
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