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A novel Dbl family RhoGEF promotes Rho-dependent axon attraction to the central nervous system midline in Drosophila and overcomes Robo repulsion

The key role of the Rho family GTPases Rac, Rho, and CDC42 in regulating the actin cytoskeleton is well established (Hall, A. 1998. Science. 279:509–514). Increasing evidence suggests that the Rho GTPases and their upstream positive regulators, guanine nucleotide exchange factors (GEFs), also play i...

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Detalles Bibliográficos
Autores principales: Bashaw, Greg J., Hu, Hailan, Nobes, Catherine D., Goodman, Corey S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199320/
https://www.ncbi.nlm.nih.gov/pubmed/11756465
http://dx.doi.org/10.1083/jcb.200110077