Cytoplasmic tail–dependent internalization of membrane-type 1 matrix metalloproteinase is important for its invasion-promoting activity

Membrane-type 1 matrix metalloproteinase (MT1-MMP) is an integral membrane proteinase that degrades the pericellular extracellular matrix (ECM) and is expressed in many migratory cells, including invasive cancer cells. MT1-MMP has been shown to localize at the migration edge and to promote cell migr...

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Detalles Bibliográficos
Autores principales: Uekita, Takamasa, Itoh, Yoshifumi, Yana, Ikuo, Ohno, Hiroshi, Seiki, Motoharu
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199326/
https://www.ncbi.nlm.nih.gov/pubmed/11756481
http://dx.doi.org/10.1083/jcb.200108112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199326/
https://www.ncbi.nlm.nih.gov/pubmed/11756481
http://dx.doi.org/10.1083/jcb.200108112

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