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Cytoplasmic tail–dependent internalization of membrane-type 1 matrix metalloproteinase is important for its invasion-promoting activity

Membrane-type 1 matrix metalloproteinase (MT1-MMP) is an integral membrane proteinase that degrades the pericellular extracellular matrix (ECM) and is expressed in many migratory cells, including invasive cancer cells. MT1-MMP has been shown to localize at the migration edge and to promote cell migr...

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Detalles Bibliográficos
Autores principales:	Uekita, Takamasa, Itoh, Yoshifumi, Yana, Ikuo, Ohno, Hiroshi, Seiki, Motoharu
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2001
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199326/ https://www.ncbi.nlm.nih.gov/pubmed/11756481 http://dx.doi.org/10.1083/jcb.200108112

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