The lipid phosphatase activity of PTEN is critical for stabilizing intercellular junctions and reverting invasiveness

To analyze the implication of PTEN in the control of tumor cell invasiveness, the canine kidney epithelial cell lines MDCKras-f and MDCKts-src, expressing activated Ras and a temperature-sensitive v-Src tyrosine kinase, respectively, were transfected with PTEN expression vectors. Likewise, the human...

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Detalles Bibliográficos
Autores principales: Kotelevets, Larissa, van Hengel, Jolanda, Bruyneel, Erik, Mareel, Marc, van Roy, Frans, Chastre, Eric
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199329/
https://www.ncbi.nlm.nih.gov/pubmed/11756467
http://dx.doi.org/10.1083/jcb.200105109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199329/
https://www.ncbi.nlm.nih.gov/pubmed/11756467
http://dx.doi.org/10.1083/jcb.200105109

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