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A regulatory cascade involving retinoic acid, Cbfa1, and matrix metalloproteinases is coupled to the development of a process of perichondrial invasion and osteogenic differentiation during bone formation

Tissue-remodeling processes are largely mediated by members of the matrix metalloproteinase (MMP) family of endopeptidases whose expression is strictly controlled both spatially and temporally. In this article, we have examined the molecular mechanisms that could contribute to modulate the expressio...

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Detalles Bibliográficos
Autores principales: Jiménez, Maria J.G., Balbín, Milagros, Alvarez, Jesús, Komori, Toshihisa, Bianco, Paolo, Holmbeck, Kenn, Birkedal-Hansen, Henning, López, José M., López-Otín, Carlos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199331/
https://www.ncbi.nlm.nih.gov/pubmed/11748248
http://dx.doi.org/10.1083/jcb.200106147