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A regulatory cascade involving retinoic acid, Cbfa1, and matrix metalloproteinases is coupled to the development of a process of perichondrial invasion and osteogenic differentiation during bone formation
Tissue-remodeling processes are largely mediated by members of the matrix metalloproteinase (MMP) family of endopeptidases whose expression is strictly controlled both spatially and temporally. In this article, we have examined the molecular mechanisms that could contribute to modulate the expressio...
Autores principales: | Jiménez, Maria J.G., Balbín, Milagros, Alvarez, Jesús, Komori, Toshihisa, Bianco, Paolo, Holmbeck, Kenn, Birkedal-Hansen, Henning, López, José M., López-Otín, Carlos |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199331/ https://www.ncbi.nlm.nih.gov/pubmed/11748248 http://dx.doi.org/10.1083/jcb.200106147 |
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