Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation

We discovered that many proteins located in the kinetochore outer domain, but not the inner core, are depleted from kinetochores and accumulate at spindle poles when ATP production is suppressed in PtK1 cells, and that microtubule depolymerization inhibits this process. These proteins include the mi...

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Detalles Bibliográficos
Autores principales: Howell, B.J., McEwen, B.F., Canman, J.C., Hoffman, D.B., Farrar, E.M., Rieder, C.L., Salmon, E.D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199338/
https://www.ncbi.nlm.nih.gov/pubmed/11756470
http://dx.doi.org/10.1083/jcb.200105093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199338/
https://www.ncbi.nlm.nih.gov/pubmed/11756470
http://dx.doi.org/10.1083/jcb.200105093

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