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Keratin 8 protection of placental barrier function

The intermediate filament protein keratin 8 (K8) is critical for the development of most mouse embryos beyond midgestation. We find that 68% of K8(−/−) embryos, in a sensitive genetic background, are rescued from placental bleeding and subsequent death by cellular complementation with wild-type tetr...

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Detalles Bibliográficos
Autores principales: Jaquemar, Daniel, Kupriyanov, Sergey, Wankell, Miriam, Avis, Jacqueline, Benirschke, Kurt, Baribault, Hélène, Oshima, Robert G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199358/
https://www.ncbi.nlm.nih.gov/pubmed/12771125
http://dx.doi.org/10.1083/jcb.200210004