Contact inhibition of VEGF-induced proliferation requires vascular endothelial cadherin, β-catenin, and the phosphatase DEP-1/CD148

Confluent endothelial cells respond poorly to the proliferative signals of VEGF. Comparing isogenic endothelial cells differing for vascular endothelial cadherin (VE-cadherin) expression only, we found that the presence of this protein attenuates VEGF-induced VEGF receptor (VEGFR) 2 phosphorylation...

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Detalles Bibliográficos
Autores principales: Lampugnani, Maria Grazia, Zanetti, Adriana, Corada, Monica, Takahashi, Takamune, Balconi, Giovanna, Breviario, Ferruccio, Orsenigo, Fabrizio, Cattelino, Anna, Kemler, Rolf, Daniel, Thomas O., Dejana, Elisabetta
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199373/
https://www.ncbi.nlm.nih.gov/pubmed/12771128
http://dx.doi.org/10.1083/jcb.200209019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199373/
https://www.ncbi.nlm.nih.gov/pubmed/12771128
http://dx.doi.org/10.1083/jcb.200209019

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