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Contact inhibition of VEGF-induced proliferation requires vascular endothelial cadherin, β-catenin, and the phosphatase DEP-1/CD148
Confluent endothelial cells respond poorly to the proliferative signals of VEGF. Comparing isogenic endothelial cells differing for vascular endothelial cadherin (VE-cadherin) expression only, we found that the presence of this protein attenuates VEGF-induced VEGF receptor (VEGFR) 2 phosphorylation...
Autores principales: | Lampugnani, Maria Grazia, Zanetti, Adriana, Corada, Monica, Takahashi, Takamune, Balconi, Giovanna, Breviario, Ferruccio, Orsenigo, Fabrizio, Cattelino, Anna, Kemler, Rolf, Daniel, Thomas O., Dejana, Elisabetta |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199373/ https://www.ncbi.nlm.nih.gov/pubmed/12771128 http://dx.doi.org/10.1083/jcb.200209019 |
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