Downregulation of an Aim-1 Kinase Couples with Megakaryocytic Polyploidization of Human Hematopoietic Cells

During the late phase of megakaryopoiesis, megakaryocytes undergo polyploidization, which is characterized by DNA duplication without concomitant cell division. However, it remains unknown by which mechanisms this process occurs. AIM-1 and STK15 belong to the Aurora/increase-in-ploidy (Ipl)1 serine/...

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Detalles Bibliográficos
Autores principales: Kawasaki, Akira, Matsumura, Itaru, Miyagawa, Jun-ichiro, Ezoe, Sachiko, Tanaka, Hirokazu, Terada, Yasuhiko, Tatsuka, Masaaki, Machii, Takashi, Miyazaki, Hiroshi, Furukawa, Yusuke, Kanakura, Yuzuru
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199624/
https://www.ncbi.nlm.nih.gov/pubmed/11266445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199624/
https://www.ncbi.nlm.nih.gov/pubmed/11266445

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