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Downregulation of an Aim-1 Kinase Couples with Megakaryocytic Polyploidization of Human Hematopoietic Cells
During the late phase of megakaryopoiesis, megakaryocytes undergo polyploidization, which is characterized by DNA duplication without concomitant cell division. However, it remains unknown by which mechanisms this process occurs. AIM-1 and STK15 belong to the Aurora/increase-in-ploidy (Ipl)1 serine/...
Autores principales: | Kawasaki, Akira, Matsumura, Itaru, Miyagawa, Jun-ichiro, Ezoe, Sachiko, Tanaka, Hirokazu, Terada, Yasuhiko, Tatsuka, Masaaki, Machii, Takashi, Miyazaki, Hiroshi, Furukawa, Yusuke, Kanakura, Yuzuru |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199624/ https://www.ncbi.nlm.nih.gov/pubmed/11266445 |
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