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Age-Related Atrophy of Motor Axons in Mice Deficient in the Mid-Sized Neurofilament Subunit

Neurofilaments are central determinants of the diameter of myelinated axons. It is less clear whether neurofilaments serve other functional roles such as maintaining the structural integrity of axons over time. Here we show that an age-dependent axonal atrophy develops in the lumbar ventral roots of...

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Detalles Bibliográficos
Autores principales: Elder, Gregory A., Friedrich, Victor L., Margita, Alla, Lazzarini, Robert A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199745/
https://www.ncbi.nlm.nih.gov/pubmed/10402469