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Transcription-dependent redistribution of the large subunit of RNA polymerase II to discrete nuclear domains

A subpopulation of the largest subunit of RNA polymerase II (Pol II LS) is located in 20-50 discrete subnuclear domains that are closely linked to speckle domains, which store splicing proteins. The speckle- associated fraction of Pol II LS is hyperphosphorylated on the COOH- terminal domain (CTD),...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199908/
https://www.ncbi.nlm.nih.gov/pubmed/7536746