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Wortmannin causes mistargeting of procathepsin D. evidence for the involvement of a phosphatidylinositol 3-kinase in vesicular transport to lysosomes
At present little is known of the biochemical machinery controlling transport of newly synthesized lysosomal hydrolases from the trans- Golgi network (TGN) to endosomes. The demonstration that Vps34p (a protein required for targeting soluble hydrolases to the vacuole in Saccharomyces cerevisiae) is...
| Formato: | Texto |
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| Lenguaje: | English |
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The Rockefeller University Press
1995
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199969/ https://www.ncbi.nlm.nih.gov/pubmed/7642698 |