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Dynamic changes in the higher-level chromatin organization of specific sequences revealed by in situ hybridization to nuclear halos
A novel approach to study the higher level packaging of specific DNA sequences has been developed by coupling high-resolution fluorescence hybridization with biochemical fractionation to remove histones and distend DNA loops to form morphologically reproducible nuclear "halos." Results dem...
| Formato: | Texto |
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| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1994
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2200020/ https://www.ncbi.nlm.nih.gov/pubmed/8034736 |