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Large-scale ruthenium- and enzyme-catalyzed dynamic kinetic resolution of (rac)-1-phenylethanol

The scale-up of the ruthenium- and enzyme-catalyzed dynamic kinetic resolution (DKR) of (rac)-1-phenylethanol (2) is addressed. The immobilized lipase Candida antarctica lipase B (CALB) was employed for the resolution, which shows high enantioselectivity in the transesterification. The ruthenium cat...

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Detalles Bibliográficos
Autores principales: Bogár, Krisztián, Martín-Matute, Belén, Bäckvall, Jan-E
Formato: Texto
Lenguaje:English
Publicado: Beilstein-Institut 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2200671/
https://www.ncbi.nlm.nih.gov/pubmed/18096033
http://dx.doi.org/10.1186/1860-5397-3-50